{"title":"RNA Synthesis \u0026 mRNA Workflow","description":"\u003cp\u003eCleavion RNA Synthesis \u0026amp; mRNA Workflow products support in vitro transcription, RNA preparation and mRNA-related research workflows. The category includes enzymes, nucleotide solutions, modified nucleotides and supporting reagents for RNA synthesis and handling.\u003c\/p\u003e\u003cp\u003eBecause RNA workflows combine enzymes and small reagent components, this collection should use filters for workflow step, reagent type, nucleotide type and pack size. Products may also appear in nucleotide or enzyme categories when relevant.\u003c\/p\u003e","products":[{"product_id":"dutp-100-mm","title":"dUTP (100 mM)","description":"DUTP, also known as 2'-deoxyuridine 5'-triphosphate, is a nucleotide essential for various biological processes. This product is prepared using ultrapure water and has a pH value of 7.0. It exhibits a high purity of ≥99% as determined by High-Performance Liquid Chromatography (HPLC) . Through rigorous testing, it has been confirmed to be free from impurities such as DNase, RNase, and phosphatases.","brand":"Cleavion","offers":[{"title":"1 mL","offer_id":57188436312439,"sku":"CLV-0014","price":98.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0014-0-cleavion-product.png?v=1781696345"},{"product_id":"dntps-10-mm-each","title":"dNTPs (10 mM each)","description":"The dNTPs premix is a pre-mixed solution containing dATP, dCTP, dGTP, and dTTP in equimolar ratios, with each nucleotide at a concentration of 10 mM. This product is prepared using ultrapure water, with a pH value adjusted to 7.0. It has a purity of ≥99% as determined by High-Performance Liquid Chromatography (HPLC) . It has been tested and found to be free from impurities such as DNase, RNase, and phosphatases.","brand":"Cleavion","offers":[{"title":"1 mL","offer_id":57188436509047,"sku":"CLV-0015","price":66.13,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0015-0-cleavion-product.png?v=1781696345"},{"product_id":"pseudo-utp-100-mm","title":"Pseudo-UTP (100 mM)","description":"(Pseudouridine) 1951, RNA, RNA“”。PseudouridinetRNA、mRNA、snRNA、snoRNA, 。KarikómRNA, mRNA。, 、、DNA、 (IVT) 、、。","brand":"Cleavion","offers":[{"title":"200 µL","offer_id":57188442603895,"sku":"CLV-0261","price":576.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0261-0-cleavion-product.png?v=1781696414"},{"product_id":"pyrophosphatase-inorganic-yeast","title":"Pyrophosphatase, Inorganic (Yeast)","description":"Pyrophosphatase, Inorganic (Yeast) is prepared from an E. coli strain with Pyrophosphatase gene from yeast. It is an enzyme that can catalyze the conversion of one molecule of pyrophosphate into two molecules of phosphate ions. This product is used in nucleic acid synthesis reactions to hydrolyze inorganic pyrophosphate generated during the reaction, thereby avoiding inhibition of the reaction and shifting the reaction equilibrium towards product formation. It can be used to increase nucleic acid yield in DNA amplification or in vitro transcription reactions. This product is active at temperatures ranging from 16 to 37°C.","brand":"Cleavion","offers":[{"title":"10 U","offer_id":57188442767735,"sku":"CLV-0262","price":84.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0262-0-cleavion-product.png?v=1781696416"},{"product_id":"pyrophosphatase-inorganic-yeast-1","title":"Pyrophosphatase, Inorganic (Yeast)","description":"Pyrophosphatase, Inorganic (Yeast) is prepared from an E. coli strain with Pyrophosphatase gene from yeast. It is an enzyme that can catalyze the conversion of one molecule of pyrophosphate into two molecules of phosphate ions. This product is used in nucleic acid synthesis reactions to hydrolyze inorganic pyrophosphate generated during the reaction, thereby avoiding inhibition of the reaction and shifting the reaction equilibrium towards product formation. It can be used to increase nucleic acid yield in DNA amplification or in vitro transcription reactions. This product is active at temperatures ranging from 16 to 37°C.","brand":"Cleavion","offers":[{"title":"100 U","offer_id":57188442931575,"sku":"CLV-0263","price":341.6,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0263-0-cleavion-product.png?v=1781696416"},{"product_id":"t7-high-yield-rna-synthesis-kit","title":"T7 High Yield RNA Synthesis Kit","description":"The T7 High Yield RNA Synthesis Kit is designed for the large-scale synthesis of RNA through in vitro transcription using T7 RNA polymerase and DNA templates containing a T7 promoter. It is suitable for both long and short RNA transcripts. The T7 Enzyme Mix included RNase inhibitor and inorganic pyrophosphatase. Additionally, DNase I, RNase-free, is provided to eliminate template DNA after the transcription reaction. Using this kit, 1 μg of linearized double-stranded DNA template can yield at least 150 μg of RNA. The synthesized RNA is applicable for a wide range of downstream applications, including in vitro translation, RNA structure and function studies, RNase protection assays, probe hybridization, RNA interference, and more.","brand":"Cleavion","offers":[{"title":"50 Reactions","offer_id":57188443095415,"sku":"CLV-0264","price":139.29,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0264-0-cleavion-product.png?v=1781696416"},{"product_id":"high-concentration-t7-rna-polymerase","title":"High-Concentration T7 RNA Polymerase","description":"T7 RNA Polymerase is derived from recombinant expression in E.coli. It is a DNA-dependent RNA polymerase that exhibits high specificity for the promoter sequence of bacteriophage T7. T7 RNA Polymerase utilizes double-stranded DNA templates containing the T7 promoter sequence and NTPs as substrates to synthesize single-stranded RNA complementary to the downstream of the promoter.","brand":"Cleavion","offers":[{"title":"20000 U","offer_id":57188443521399,"sku":"CLV-0287","price":464.45,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0287-0-cleavion-product.png?v=1781696418"},{"product_id":"polya-rna-polymerase-for-mrna-tailing","title":"Poly(A) RNA Polymerase for mRNA Tailing","description":"Poly (A) Polymerase is a polymerase derived from Escherichia coli, also known as E.coli PAP, PAP enzyme, Poly (A) tailing enzyme, or PolyA tailing enzyme. Poly (A) Polymerase catalyzes the rapid and efficient addition of a poly (A) tail to the 3' end of single-stranded RNA (ssRNA) in the presence of ATP. It can use various single-stranded RNA as substrate, while double-stranded RNA and excessively short oligonucleotides (\u0026lt;20 nt) are not recommended as substrates. DNA cannot be used as substrates for this enzyme. Poly (A) tailing reaction catalyzed by E. coli Poly (A) Polymerase can only use ATP, but not ADP or dATP. In addition, when CTP and UTP are used, the incorporation amount is less than 5% of that when using ATP. GTP can not be used by this enzyme.","brand":"Cleavion","offers":[{"title":"100 U","offer_id":57188443685239,"sku":"CLV-0288","price":140.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0288-0-cleavion-product.png?v=1781696418"},{"product_id":"polya-rna-polymerase-for-mrna-tailing-1","title":"Poly(A) RNA Polymerase for mRNA Tailing","description":"Poly (A) Polymerase is a polymerase derived from Escherichia coli, also known as E.coli PAP, PAP enzyme, Poly (A) tailing enzyme, or PolyA tailing enzyme. Poly (A) Polymerase catalyzes the rapid and efficient addition of a poly (A) tail to the 3' end of single-stranded RNA (ssRNA) in the presence of ATP. It can use various single-stranded RNA as substrate, while double-stranded RNA and excessively short oligonucleotides (\u0026lt;20 nt) are not recommended as substrates. DNA cannot be used as substrates for this enzyme. Poly (A) tailing reaction catalyzed by E. coli Poly (A) Polymerase can only use ATP, but not ADP or dATP. In addition, when CTP and UTP are used, the incorporation amount is less than 5% of that when using ATP. GTP can not be used by this enzyme.","brand":"Cleavion","offers":[{"title":"500 U","offer_id":57188443881847,"sku":"CLV-0289","price":438.8,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0289-0-cleavion-product.png?v=1781696420"},{"product_id":"t7-rna-polymerase-gmp-grade","title":"T7 RNA Polymerase, GMP Grade","description":"T7 RNA Polymerase, GMP Grade is derived from recombinant expression in E.coli. lt is a DNA-dependent RNA polymerase that exhibits high specificity for the promoter sequence of bacteriophage T7. T7 RNA Polymerase utilizes double-stranded DNA templates containing the T7 promoter sequence and NTPs as substrates to synthesize single-stranded RNA complementary to the downstream of the promoter. This product is manufactured and quality-controlled in compliance with GMP specifications, ensuring full traceability of the production process and raw materials. The entire production process does not involve the use of antibiotics or any animal-derived materials and excipients. Stringent controls are implemented for process-related impurities including host proteins, exogenous DNA, non-specific endonucleases, DNase, RNase, as well as microbial limits and bacterial endotoxins. This product meets the requirements for raw materials in fields such as vaccine and pharmaceutical production.","brand":"Cleavion","offers":[{"title":"20000 U","offer_id":57188443914615,"sku":"CLV-0249","price":536.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0249-0-cleavion-product.png?v=1781696421"},{"product_id":"t7-rna-polymerase-gmp-grade-1","title":"T7 RNA Polymerase, GMP Grade","description":"T7 RNA Polymerase, GMP Grade is derived from recombinant expression in E.coli. lt is a DNA-dependent RNA polymerase that exhibits high specificity for the promoter sequence of bacteriophage T7. T7 RNA Polymerase utilizes double-stranded DNA templates containing the T7 promoter sequence and NTPs as substrates to synthesize single-stranded RNA complementary to the downstream of the promoter. This product is manufactured and quality-controlled in compliance with GMP specifications, ensuring full traceability of the production process and raw materials. The entire production process does not involve the use of antibiotics or any animal-derived materials and excipients. Stringent controls are implemented for process-related impurities including host proteins, exogenous DNA, non-specific endonucleases, DNase, RNase, as well as microbial limits and bacterial endotoxins. This product meets the requirements for raw materials in fields such as vaccine and pharmaceutical production.","brand":"Cleavion","offers":[{"title":"200000 U","offer_id":57188444078455,"sku":"CLV-0250","price":4154.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0250-0-cleavion-product.png?v=1781696421"},{"product_id":"t7-rna-polymerase","title":"T7 RNA Polymerase","description":"T7 RNA Polymerase is derived from recombinant expression in E.coli. It is a DNA-dependent RNA polymerase that exhibits high specificity for the promoter sequence of bacteriophage T7. T7 RNA Polymerase utilizes double-stranded DNA templates containing the T7 promoter sequence and NTPs as substrates to synthesize singlestranded RNA complementary to the downstream of the promoter.","brand":"Cleavion","offers":[{"title":"5000 U","offer_id":57188444275063,"sku":"CLV-0251","price":105.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0251-0-cleavion-product.png?v=1781696421"},{"product_id":"t7-rna-polymerase-1","title":"T7 RNA Polymerase","description":"T7 RNA Polymerase is derived from recombinant expression in E.coli. It is a DNA-dependent RNA polymerase that exhibits high specificity for the promoter sequence of bacteriophage T7. T7 RNA Polymerase utilizes double-stranded DNA templates containing the T7 promoter sequence and NTPs as substrates to synthesize singlestranded RNA complementary to the downstream of the promoter.","brand":"Cleavion","offers":[{"title":"25000 U","offer_id":57188444438903,"sku":"CLV-0252","price":309.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0252-0-cleavion-product.png?v=1781696422"},{"product_id":"high-t7-rna-polymerase","title":"High T7 RNA Polymerase","description":"High T7 RNA Polymerase is a genetically engineered thermostable T7 RNA polymerase, which exhibits high specificity for the bacteriophage T7 promoter sequence. Compared to the wild-type T7 RNA polymerase, High T7 RNA Polymerase enables efficient in vitro transcription (IVT) at temperature from 37 to 52°C.","brand":"Cleavion","offers":[{"title":"5000 U","offer_id":57188444635511,"sku":"CLV-0253","price":128.75,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0253-0-cleavion-product.png?v=1781696423"},{"product_id":"high-t7-rna-polymerase-1","title":"High T7 RNA Polymerase","description":"High T7 RNA Polymerase is a genetically engineered thermostable T7 RNA polymerase, which exhibits high specificity for the bacteriophage T7 promoter sequence. Compared to the wild-type T7 RNA polymerase, High T7 RNA Polymerase enables efficient in vitro transcription (IVT) at temperature from 37 to 52°C.","brand":"Cleavion","offers":[{"title":"25000 U","offer_id":57188444799351,"sku":"CLV-0254","price":390.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0254-0-cleavion-product.png?v=1781696424"},{"product_id":"utp-100-mm","title":"UTP (100 mM)","description":"UTP, also known as Uridine-5'-Triphosphate, is a colorless and transparent aqueous solution with a purity of ≥99% (HPLC) . It is free from DNase, RNase, and phosphatase contamination. It is primarily used in in vitro transcription (IVT), aptamer, laboratory-developed tests (LDT), analyte-specific reagents (ASR), PCR, and RT-PCR reactions.","brand":"Cleavion","offers":[{"title":"1 mL","offer_id":57188445487479,"sku":"CLV-0258","price":106.92,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0258-0-cleavion-product.png?v=1781696426"},{"product_id":"ntp-bundle-25-mm-each","title":"NTP Bundle (25 mM each)","description":"The product is a high-purity NTP Tris-HCl solution, containing 25 mM each of ATP, CTP, GTP, and UTP. It is a colorless and transparent aqueous solution, free from DNase, RNase, and phosphatase contamination. It is primarily used in in vitro transcription (IVT), aptamer, laboratory-developed tests (LDT), analyte-specific reagents (ASR), PCR, and RT-PCR reactions.","brand":"Cleavion","offers":[{"title":"1 mL","offer_id":57188445618551,"sku":"CLV-0259","price":120.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0259-0-cleavion-product.png?v=1781696427"},{"product_id":"n1-methyl-pseudo-utp-100-mm","title":"N1-Methyl-Pseudo-UTP (100 mM)","description":"","brand":"Cleavion","offers":[{"title":"100 µL","offer_id":57188445749623,"sku":"CLV-0260","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0991\/7097\/6119\/files\/CLV-0260-0-cleavion-product.png?v=1781696428"}],"url":"https:\/\/quantimol.myshopify.com\/collections\/rna-synthesis-mrna-workflow.oembed?page=2","provider":"Cleavion","version":"1.0","type":"link"}